S.LSC.5.01 Genetics

1. DNA Recombination (5) a. Forms of recombination: site-specific and illegitimate b. Model for Homologous Recombination: Holliday Model c. Gene conversion 2. Mobile Genetic Elements (5) a. Overview b. Transposable elements in bacteria: IS element c. Transposable elements in eukaryotes: Ac element in maize d. Transposable elements in humans: LINES, SINES e. Evolutionary significance of transposable elements 3. Cancer Genetics (5) a. Overview of Cancer cells -Characteristics of cancer cells b. Types and causes of cancer c. Viruses and cancer d. Proto-oncogenes and Oncogenes-Ras e. Tumour suppressor genes- p53